Artificial sweeteners are toxic to digestive system, study reveals

* Several FDA-approved products could be harmful to consumers ─Researchers

*Consumption of artificial sweeteners adversely affects gut microbial activity

Isola Moses | ConsumerConnect

A recent study into certain foods and drinks has found that several artificial sweeteners, all of which are approved by the US Food and Drug Administration (FDA), are toxic to consumers’ digestive system.

Report says the sweeteners, which include aspartame, acesulfame potassium-K, neotame, advantame, saccharine, and sucralose, and 10 sports supplements that contain these flavours, have gained popularity because they don’t have as much sugar.

However, many people are unaware the foods and drinks they’re consuming have these sweeteners in them, according to ConsumerAffairs.

Prof. Ariel Kushmaro and John A. Ungar, Chairman of Biotechnology Engineering in Stella Goldstein-Goren Department of Biotechnology Engineering, said: “The results of this study might help in understanding the relative toxicity of artificial sweeteners and the potential negative effects on the gut microbial community, as well as the environment.”

Stressing that such artificial sweeteners are toxic to human digestive system, the researchers from Ben Gurion University used bioluminescent bacteria from E. coli to test the effects of the six sweeteners and the 10 sports supplements on the digestive system.

Prof. Kushmaro stated that “we modified bioluminescent E. coli bacteria, which luminesce when they detect toxicants, and act as a sensing model representative of the complex microbial system.”

After interacting with just one mg/ml of the sweeteners, the bacteria in the digestive system was found to be toxic, said the report.

“This is further evidence that consumption of artificial sweeteners adversely affects gut microbial activity, which can cause a wide range of health issues,” said Kushmaro.

The study noted that artificial sweeteners are making headlines in the media, as the effects they have on consumers’ health continue to be a popular area of research.

Many of the findings from previous studies have been inconclusive or conflicting.

While many are drawn to the promise of lower calories, researchers have found some health risks associated with the flavourings.

In April 2020, a study found that consuming low-calorie, artificial sweetener in excess could cause your body to accumulate more fat.

Dr. Sabyasachi Sen, an Associate Professor of Medicine and Endocrinology at George Washington University, United States, and lead researcher in the study, stated: “From our study, we believe that low-calorie sweeteners promote additional fat formation by allowing more glucose to enter the cells, and promotes inflammation, which may be more detrimental in obese individuals.”

According to the report, medical professional Sen was particularly concerned because these findings were more prominent in people who were already obese and consuming the low-calorie sweetener in an effort at losing weight.

People with diabetes or pre-diabetes were also exposed to increased risk due to the increase of glucose in the cells, he affirmed.

However, where weight loss is concerned, a study at the end of 2016 found that in the short-term, deciding between sugary beverages and beverages with artificial sweetener produce the same result.

The study also discovered that insulin levels, daily energy, and glucose levels remained the same for all 30 male participants in their trial, regardless of whether they consumed a beverage with sugar, aspartame (a plant-derived artificial sweetener), or monk fruit. The researchers believe the reason to be that the food consumed throughout the day made up for the calories not found in the artificially-sweetened beverages.

Nonetheless, a key finding was the short-term nature of this study, as the researchers did note that artificial sweeteners do affect body weight and energy levels in the long-term.

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